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Pharmacologie  [5 offres]
165653 Pharmacokinetics Researcher (Pharmaceutical Analysis) (Offre rédigée en anglais seulement)

Date limite

2 mai 2024

Description du poste

You will have the opportunity to participate domestic and international pharmaceutical conferences and communicate with experts in the industry.

Job responsibility

In vitro pharmacokinetics direction:

1. Use in vitro models or related biological substrates (plasma, cells, microsomes, buffer, etc.) to conduct in vitro screening tests of drug candidates, including physical and chemical properties, drug distribution, drug metabolism and drug-drug interaction;

2, Perform sample analysis using high performance liquid phase and triple quadrupole mass spectrometry tandem technology and high-resolution mass spectrometer;

3. Design and carry out in vitro drug metabolism experiments, collect and sort out experimental data, and prepare experimental protocols and reports.

in vivo Pharmacokinetic:

1. Using LC-MS to analyze drugs and metabolites in biological samples (animal blood, tissues, etc.) and conduct PK/PD correlation research;

2, the use of analytical instruments (HPLC, LC/MS/MS) to examine the reaction of the efficacy in the body, the detection of the drug concentration;

3. Design and carry out in vivo drug metabolism experiments, collect and sort out experimental data, and prepare experimental protocols and reports.

Job requirements

1, Pharmacy, pharmacology, pharmaceutical analysis, drug metabolism, pharmaceutical chemistry, natural pharmaceutical chemistry, biology or other related major or research direction, doctoral degree;

2. Familiar with the process of new drug research and development, solid professional knowledge and theoretical foundation, proficient in liquid chromatography-mass spectrometry and other related technologies, familiar with the design and operation of preclinical pharmacokinetic experimental schemes, pharmacokinetic software and calculation methods;

3, love the pharmaceutical research and development industry, with fast learning ability and adaptability, good analytical skills, communication and coordination skills and team spirit, leadership, a strong sense of responsibility.

4, with good scientific research ability, able to independently undertake projects, develop project plans, and lead the team to solve problems in the project;

5, English and Chinese proficiency, good English communication, reading English literature and writing English experimental plan ability.

Conditions

Lieu de travail : Région de Montréal , Beijing, Ningbo

Statut d'emploi: Permanent

Type d'emploi: Temps plein (8 heures)

Date d'entrée en fonction: Immédiatement

Salaire : Minimum is 300k RMB/Year

Autre(s) avantage(s): n/d

Exigences

Être diplomé

Catégorie(s) :

Recherche

Discipline(s) d'études :

Biochimie

Biologie moléculaire

Chimie

Développement du médicament

Microbiologie et immunologie

Pathologie et biologie cellulaire

Pharmacologie

Sciences biomédicales / Génie biomédical

Cycle(s) d'études : Doctorat

Exigence(s) linguistique(s) : Chinese

Autre(s) exigence(s) : n/d

165651 Biology Researcher (offre rédigée en anglais seulement)

Date limite

2 mai 2024

Description du poste

Scientist for early target discovery, in vitro biological method development and screening evaluation in the research and development of small molecular drugs. Scientist will be integrated into the existing technology research and development platform, to cooperate with neighbouring departments of Pharmaron, such as pharmaceutical chemistry, pharmacokinetics, in vivo pharmacology, to serve customers for novel drug discovery. Will participate in the communication and cooperation of Pharmaron global research and development team. You may also have the opportunity to participate in and be responsible for the exchange and development of drug research projects of multinational pharmaceutical companies.

 

Job responsibility

Responsible for the evaluation of drug activity at the cellular level, in vitro cell culture, cell model building and related molecular experiments;

2. Responsible for the optimization and development of enzymatic methods and the evaluation of drug activity, involving a variety of enzymes and multi-mode technical methods;

3. Collect, summarize and sort out experimental data and write relevant reports; Needs to be able to read English experimental protocols and report experimental progress and anomalies to the client.

Conditions

Lieu de travail : International , Beijing Headquarters, Beijing Changping,

Statut d'emploi: Permanent

Type d'emploi: Temps plein

Date d'entrée en fonction: Immédiatement

Salaire : Minimum is 300k RMB/Year

Autre(s) avantage(s): We have free hair salon,free on site Gym-free fitness class, free parking, meal subsidy.... different work site have different benefit, for more information, please talk with HR

Exigences

Être étudiant ou diplômé

Catégorie(s) :

Génie

Recherche

Discipline(s) d'études :

Biochimie

Bio-informatique

Biologie moléculaire

Microbiologie et immunologie

Pathologie et biologie cellulaire

Pharmacologie

Sciences biologiques

Sciences biomédicales / Génie biomédical

Cycle(s) d'études : Doctorat

Exigence(s) linguistique(s) : Anglais parlé. Anglais écrit. Chinese

Autre(s) exigence(s) :

 

Job requirements

1. Clear thinking, good at communication and teamwork;

2. Proficient in molecular biology, cell biology (cell engineering, flow cytometry, drug screening), enzymology (content development), immunology (T cell, B cell, NK cell related experience), biological products and nanomedicine development experience, proteomics routine experimental technology, in vitro pharmacology, target-dependent drug screening experience is preferred;

3. Should be able to undertake a scientific project independently, make the project plan, and lead the team to solve the problems in the project;

4. Should be proficient in English and Chinese, and able to read English literature and write English experimental protocols.

165650 Process Development (offre rédigée en anglais seulement)

Date limite

2 mai 2024

Description du poste

You will be engaged in the research and development of biopharmaceuticals; Focus on the research and development of formulations and production processes for biopharmaceuticals; Have the opportunity to access current industry-leading technology platforms and lead innovative trends in drug discovery; Have the opportunity to have face-to-face communication and learning with experts from multinational pharmaceutical companies.

 

1. Participate in the construction of drug product (DP) development laboratories and platforms;

2. Participate in formulations and production processes development, developability, and combination products for biopharmaceuticals.

3. Fill in relevant experimental records in a timely and truthful manner, and complete data collation and report summary in a timely manner after the experiment is completed.

4. Participate in the maintenance and calibration of laboratory instruments and equipment;

5. Participate in the ordering, tracking, and requisition of laboratory instruments, consumables, and reagents

Conditions

Lieu de travail : International , Ningbo

Statut d'emploi: Permanent

Type d'emploi: Temps plein (8 heures)

Date d'entrée en fonction: Immédiatement

Salaire : Minimum is 300k RMB/Year

Autre(s) avantage(s): We have free hair salon,free on site Gym-free fitness class, free parking, meal subsidy.... different work site have different benefit, for more information, please talk with HR

Exigences

Être étudiant ou diplômé

Catégorie(s) :

Recherche

Discipline(s) d'études :

Biochimie

Pharmacologie

Sciences biomédicales / Génie biomédical

Cycle(s) d'études : Doctorat

Exigence(s) linguistique(s) : Anglais parlé. Anglais écrit. Chinese

Autre(s) exigence(s) :

 

Job requirements

1. Pharmaceutics, biochemistry, biotechnology and bioengineering and related majors, doctor degree;

2. Familiar with the development principles and basic requirements of sterile injections, as well as the formulation-related analysis methods;

3. Being down-to-earth and hardworking, patient and meticulous, self-motivated, and have a strong sense of progress;

4. Fluent English and Chinese; Strong learning and understanding abilities, be good at thinking problems;

5. Have strong hands-on experiment experience and communication skills;

6. Being able to work in a team and enjoy laboratory work.

Career Development:

1. Through professional and systematic training, grow into technical experts in industry;

2. Explore your management potential, have the opportunity to be promoted to a management position, and receive equity incentives.

165648 Researcher in Chemical Analysis (Pharmaceutical Analysis) (offre rédigée en anglais seulement)

Date limite

2 mai 2024

Description du poste

You will be engaged in the analysis of small-molecule drugs,primarily focusing on testing by using analytical instruments,method development,and validation. This role provides an opportunity to work with advanced technology platforms and lead the pharmaceutical discovery trends. You will also have the chance to engage in face-to-face exchanges with pharmaceutical experts from multinational companies.

Conditions

Lieu de travail : International , Beijing,Ningbo,Tianjin,Xi 'an,Qingdao,Ch

Statut d'emploi: Permanent

Type d'emploi: Temps plein (8 heures)

Date d'entrée en fonction: Immédiatement

Salaire : Minimum is 300k RMB/Year

Autre(s) avantage(s): We have free hair salon,free on site Gym-free fitness class, free parking, meal subsidy.... different work site have different benefit, for more information, please talk with HR

Exigences

Être étudiant ou diplômé

Discipline(s) d'études :

Chimie

Pharmacologie

Cycle(s) d'études : Doctorat

Exigence(s) linguistique(s) : Anglais parlé. Anglais écrit. Chinese

Autre(s) exigence(s) :

  • Utilize various analytical methods such as HPLC, UPLC, LC-MS, GC, GC-MS, IC, ICP-MS, HR-MS, etc., to provide objective, accurate, and timely analysis data for Medicinal Chemistry, Synthetic Chemistry, and Discovery Process Chemistry.
  • Provide professional and rapid chiral analysis and separation services using chromatographic techniques such as HPLC or SFC. Purify mixtures provided by Medicinal Chemistry, Synthetic Chemistry, and Library using various chromatographic separation techniques such as Prep-HPLC.
  • Understand basic instrument maintenance, perform regular instrument maintenance, and conduct trouble shooting for minor issues.
  • Conduct and complete experimental research reports in a timely manner according to company requirements.
  • Job Requirements
  • Possess a Ph.D. degree in Analytical Chemistry, Pharmacy, or a related field, with a strong foundation in analytical chemistry and organic chemistry;
  • Demonstrate proficiency in operating instruments such as Prep-HPLC, Flash, LCMS, and other relevant equipment;
  • Exhibit excellent communication skills and a collaborative spirit to effectively interact with colleagues and contribute to a team environment;
  • Have good Chinese and English skills to support effective communication and presentation of scientific information;
  • Adhere to relevant safety regulations and protocols in order to maintain a safe working environment;
  • Adapt to a fast-paced work environment and have the ability work under high pressure.

165647 QC Scientist, Pharmaron Biologics (offre rédigée en anglais seulement)

Date limite

2 mai 2024

Description du poste

Responsible for QC sample testing and release as well as problem solving, as an expert in QC analysis methods, lead the transfer, validation and optimization of analysis methods.

Responsibilities

As an expert in QC methods, you are responsible for researching and understanding the principles of basic QC testing methods, instrument principles and being able to promptly identify and solve QC method problems.

Implement and follow QC laboratory GMP standard operating procedures to complete the testing tasks of raw materials and products, write and upgrade QC testing methods, record testing data on time, complete corresponding reports, and ensure the truth and integrity of data.

To participate in the establishment of quality specifications for raw materials and products, and provide scientific justification for the establishment of quality specifications.

Participate in OOS/OOT and deviation investigation in the laboratory

Support internal/external and regulatory agency audits.

Lead method transfer and validation activities.

Support QC project management.

Interaction and collaboration with analytical development department or third party services.

Conditions

Lieu de travail : International , Ningbo

Statut d'emploi: Permanent

Type d'emploi: Temps plein (8 heures)

Date d'entrée en fonction: Immédiatement

Salaire : Minimum is 300k RMB/Year

Autre(s) avantage(s): We have free hair salon,free on site Gym-free fitness class, free parking, meal subsidy.... different work site have different benefit, for more information, please talk with HR

Exigences

Être étudiant ou diplômé

Catégorie(s) :

Recherche

Génie

Offres générales exigeants des études universitaires

Discipline(s) d'études :

Biochimie

Biologie moléculaire

Développement du médicament

Pharmacologie

Sciences biologiques

Sciences biomédicales / Génie biomédical

Cycle(s) d'études : Doctorat

Exigence(s) linguistique(s) : Anglais écrit.

Autre(s) exigence(s) :

PhD in basic science or engineering, with a certain level of knowledge in the field of biopharmaceuticals is preferred

Have a certain depth of hands-on ability and problem solving experience in physicochemical or biochemical analysis methods and in vitro cell detection.

Proficient in common protein analysis methods, biological activity detection methods, as well as their methodology and applications.

Having experience in various (or partial) analytical techniques such as HPLC, CE, cIEF, ELISA, LC-MS, ELISA, biossay, osmolarity, endotoxin, moisture content (Karl Fischer), TOC, particle analysis of injected drugs, and process impurity analysis (rDNA, rHCP, rProA).

Understand the production process of biopharmaceuticals, especially monoclonal antibodies.

Having good teamwork, communication, and organizational skills.

Proficient in both Chinese and English.